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Cyclic Neutropenia is a stem cell disease, which is characterised by cyclic fluctuations in leukocyte numbers, especially the neutrophils.
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Spezifikationen
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Tupfer, EDTA Blut, Heparin Blut, Sperma, Gewebe |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Allgemeine Informationen
Cyclic Neutropenia is a stem cell disease, which is characterised by cyclic fluctuations in leukocyte numbers, especially the neutrophils.
In dogs the disease is also known as cyclic hematopoiesis or Grey/Gray Collie Syndrom. In humans known as Hermansky-Pudlak Syndrome 2 (HPS-2).
Klinische Merkmale
Affected animals have an associated coat colour dilution, causing a gray coat colour. The cyclic neutropenia is associated with symptoms as recurrent fever, anorexia and severe - often life threathening - infections.
Zusätzliche Information
Verweise
Pubmed ID: 12897784
Omia ID: 248